Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute

The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.

IJMS, Free Full-Text

Martina MALNAR, PostDoc, PhD

Solving neurodegeneration: common mechanisms and strategies for

Silva Katusic Hecimovic - Senior Scientist - Ruđer Bošković

Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C

The pathogenesis of Niemann–Pick type C disease: a role for

Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C

Finding pathogenic commonalities between Niemann-Pick type C and

Solving neurodegeneration: common mechanisms and strategies for