Therapeutic implications of menin inhibition in acute leukemias
Por um escritor misterioso
Last updated 29 junho 2024
![Therapeutic implications of menin inhibition in acute leukemias](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41375-021-01309-y/MediaObjects/41375_2021_1309_Fig2_HTML.png)
![Therapeutic implications of menin inhibition in acute leukemias](https://ascopubs.org/na101/home/literatum/publisher/asco/journals/content/edbk/2022/edbk.2022.42/edbk_349605/20230421/images/large/edbk_349605-table2.jpeg)
Contemporary Approach to Acute Myeloid Leukemia Therapy in 2022
![Therapeutic implications of menin inhibition in acute leukemias](https://www.future-science.com/cms/10.4155/fmc.13.214/asset/images/medium/figure1.gif)
Challenges and opportunities in targeting the menin–MLL
![Therapeutic implications of menin inhibition in acute leukemias](https://pubs.acs.org/cms/10.1021/acs.jmedchem.1c00872/asset/images/medium/jm1c00872_0022.gif)
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
![Therapeutic implications of menin inhibition in acute leukemias](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs12185-012-1180-0/MediaObjects/12185_2012_1180_Fig4_HTML.gif)
Disordered epigenetic regulation in MLL-related leukemia
![Therapeutic implications of menin inhibition in acute leukemias](https://biomeafusion.com/wp-content/uploads/2023/09/Biomea-Pipeline-Q3-2023.png)
Pipeline - Biomea Fusion
![Therapeutic implications of menin inhibition in acute leukemias](https://europepmc.org/articles/PMC8752621/bin/41408_2021_603_Fig5_HTML.jpg)
Effective Menin inhibitor-based combinations against AML with MLL
![Therapeutic implications of menin inhibition in acute leukemias](https://www.researchgate.net/publication/369266906/figure/fig3/AS:11431281131498145@1680144991830/MEN1-mutations-confer-resistance-to-menin-inhibitor-treatment-in-vitro-a-b-Dose-response.png)
MEN1 mutations confer resistance to menin inhibitor treatment in
![Therapeutic implications of menin inhibition in acute leukemias](https://onlinelibrary.wiley.com/cms/asset/8bc78261-51e0-4050-b6b8-c60dbae96d7a/ajh26989-fig-0001-m.jpg)
American Journal of Hematology, Blood Research Journal
![Therapeutic implications of menin inhibition in acute leukemias](https://www.thelancet.com/cms/attachment/297479dd-4f34-413b-a705-5e34af73968e/gr1_lrg.jpg)
Acute myeloid leukaemia - The Lancet
![Therapeutic implications of menin inhibition in acute leukemias](https://ars.els-cdn.com/content/image/1-s2.0-S1535610815001002-gr1.jpg)
Designed to Kill: Novel Menin-MLL Inhibitors Target MLL-Rearranged
![Therapeutic implications of menin inhibition in acute leukemias](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs12935-023-02877-y/MediaObjects/12935_2023_2877_Fig3_HTML.png)
A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression
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