CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids
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Last updated 22 junho 2024
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://www.cell.com/cms/attachment/eea8ce0e-5d6d-4f9b-88a4-f317680697a5/gr4_lrg.jpg)
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PDF) Establishing induced pluripotent stem cell lines from two
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://i1.rgstatic.net/publication/361068074_Modelling_autosomal_dominant_optic_atrophy_associated_with_OPA1_variants_in_iPSC-derived_retinal_ganglion_cells/links/62ad2c09a920e8693efd15fd/largepreview.png)
PDF) Modelling autosomal dominant optic atrophy associated with
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://www.cell.com/cms/attachment/1cd5d231-d33c-4bde-bd35-df5367f63f4d/gr4_lrg.jpg)
OPA1 regulation of mitochondrial dynamics in skeletal and cardiac
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Melatonin Repairs Osteoporotic Bone Defects in Iron-Overloaded
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CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://ars.els-cdn.com/content/image/1-s2.0-S2213671122001588-fx1.jpg)
Functional genomics and the future of iPSCs in disease modeling
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://www.mdpi.com/ijms/ijms-24-03019/article_deploy/html/images/ijms-24-03019-g004-550.jpg)
IJMS, Free Full-Text
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CRISPR/Cas9-mediated A4GALT suppression rescues Fabry disease
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Characterisation of a novel OPA1 splice variant resulting in
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://ars.els-cdn.com/content/image/1-s2.0-S1931524423000257-gr2.jpg)
CRISPR/Cas9-mediated A4GALT suppression rescues Fabry disease
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://onlinelibrary.wiley.com/cms/asset/4efe2cfb-932e-4a02-a79f-0eea690b3406/ctm2954-fig-0008-m.jpg)
Metabolic rescue ameliorates mitochondrial encephalo
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://i1.rgstatic.net/publication/370129626_OPA1_Dominant_Optic_Atrophy_Pathogenesis_and_Therapeutic_Targets/links/6447c3518ac1946c7a4d6278/largepreview.png)
PDF) OPA1 Dominant Optic Atrophy: Pathogenesis and Therapeutic Targets
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://www.frontiersin.org/files/MyHome%20Article%20Library/1251216/1251216_Thumb_400.jpg)
Frontiers Establishing induced pluripotent stem cell lines from
![CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs: Molecular Therapy - Nucleic Acids](https://www.liebertpub.com/cms/10.1089/crispr.2021.0110/asset/images/medium/crispr.2021.0110_figure3.jpg)
CRISPR-AsCas12a Efficiently Corrects a GPR143 Intronic Mutation in
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