Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia
Por um escritor misterioso
Last updated 29 junho 2024
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fnchembio.773/MediaObjects/41589_2012_Article_BFnchembio773_Fig1_HTML.jpg)
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Frontiers Pharmacologic Targeting of Chromatin Modulators As
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://onlinelibrary.wiley.com/cms/asset/ea778c15-b062-4d94-808c-580ecd8abc64/cas15054-fig-0002-m.jpg)
Leukemogenesis via aberrant self‐renewal by the MLL/AEP‐mediated
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://ars.els-cdn.com/content/image/1-s2.0-S1535610815000665-gr4.jpg)
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://pubs.acs.org/cms/10.1021/acs.jmedchem.1c00872/asset/images/large/jm1c00872_0023.jpeg)
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://pubs.acs.org/cms/10.1021/acs.jmedchem.1c00872/asset/images/large/jm1c00872_0002.jpeg)
Recent Progress of Small Molecule Menin–MLL Interaction Inhibitors
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://www.future-science.com/cms/10.4155/fmc.13.214/asset/images/medium/figure6.gif)
Challenges and opportunities in targeting the menin–MLL
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://ars.els-cdn.com/content/image/1-s2.0-S1535610815000665-gr3.jpg)
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://ars.els-cdn.com/content/image/1-s2.0-S1535610815000665-gr5.jpg)
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://files.rcsb.org/pub/pdb/validation_reports/gq/4gq6/4gq6_multipercentile_validation.png)
RCSB PDB - 4GQ6: Human menin in complex with MLL peptide
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://onlinelibrary.wiley.com/cms/asset/a99c9776-c1b3-4692-b69e-3d239650f2b3/mfig001.jpg)
Menin as a hub controlling mixed lineage leukemia - Thiel - 2012
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://media.springernature.com/m685/springer-static/image/art%3A10.1007%2Fs12185-012-1180-0/MediaObjects/12185_2012_1180_Fig2_HTML.gif)
Disordered epigenetic regulation in MLL-related leukemia
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://i1.rgstatic.net/publication/221785705_Menin-MLL_Inhibitors_Reverse_Oncogenic_Activity_of_MLL_Fusion_Proteins_in_Leukemia/links/09e41511264ef1c016000000/largepreview.png)
PDF) Menin-MLL Inhibitors Reverse Oncogenic Activity of MLL Fusion
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://www.mdpi.com/ijms/ijms-23-02362/article_deploy/html/images/ijms-23-02362-g001-550.jpg)
IJMS, Free Full-Text
![Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia](https://ars.els-cdn.com/content/image/1-s2.0-S1535610815000665-gr7.jpg)
Pharmacologic Inhibition of the Menin-MLL Interaction Blocks
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